Wellbutrin Bipolar: Wellbutrin is an antidepressant drug frequently administered by doctors to treat depression in individuals with bipolar illness. With fewer adverse effects, this drug can be as helpful as other antidepressants.

Wellbutrin is frequently prescribed to treat depression in adults, including those who suffer from bipolar disorder. It can treat effectively while avoiding some of the frequent adverse effects of other antidepressants, such as decreased libido.

The questions you should ask your doctor about the risks and benefits of using Wellbutrin to treat bipolar illness are covered in this article. It also addresses what to ask about initiating Wellbutrin, interactions, and typical Wellbutrin side effects for bipolar illness.

What is Bipolar Wellbutrin?

An unusual antidepressant is Wellbutrin. This indicates that, in contrast to traditional antidepressants that target a single mechanism, it treats depression in a variety of methods. There are two distinct tablet forms of Wellbutrin: extended release (ER or XL) and sustained release (SR).

The Food and Drug Administration (FDA) has authorized the use of Wellbutrin XL and Wellbutrin SR for the treatment of adult depression. In addition to preventing seasonal affective disorder (SAD), Wellbutrin XL is also authorized by the FDA.

What Is the Mechanism of Action of Wellbutrin in The Treatment of Bipolar Illness?

Wellbutrin’s active component, bupropion, raises the amount of norepinephrine and dopamine in the brain. These substances act as both neurotransmitters and hormones, controlling our emotions and moods.

Bipolar disorder can cause mood swings, which might include bouts of depression or persistent sadness. Bupropion maintains dopamine and norepinephrine levels stable. This may help those with bipolar disorder manage and lessen their depressive symptoms.

The severity of symptoms was markedly reduced by bupropion in a 2016 study of its usage in the treatment of bipolar illness. Additionally, the study discovered that bupropion had comparable effects to other antidepressants. Find out more about your choices for treating bipolar disorder.

What Are the Criteria for Beginning Wellbutrin Treatment for Bipolar Disorder?

The Food and Drug Administration (FDA) has not licensed Wellbutrin for the treatment of bipolar illness. With this ailment, though, your doctor could still recommend it for off-label usage.

Medication prescribed for indications not approved by the FDA is considered off-label. This is a lawful and prevalent practice. Ask your doctor if they would suggest using Wellbutrin off-label.

Wellbutrin SR oral pills are available in 100-mg (blue), 150-mg (purple), and 200-mg (light pink) dosages. Wellbutrin XL is available in 150 mg and 300 mg oral tablets, all of which are white. Wellbutrin is a medication that your doctor may prescribe for bipolar disorder. They will tell you the dosage they suggest and how frequently you should take it.

What Possible Hazards Does Wellbutrin Pose to Those with Bipolar Illness?

Although uncommon, Wellbutrin can have significant adverse effects. If you experience any of the following, be sure to seek emergency assistance and call your physician.

Phase change

Changing phases between the different states of bipolar disorder. A 2019 study of two individuals suffering from bipolar depression indicates that bupropion may cause a manic or hypomanic episode.

According to a 2016 meta-analysis, the rates of phase shifting between bupropion and other antidepressants were comparable. Notably, there is no proof of a causal link between bupropion and mania.

The danger of phase shifting with bupropion, the active component of Wellbutrin, is not now known. For this reason, you should discuss the potential advantages and hazards of beginning Wellbutrin with your physician. If you notice any phase shifting while taking Wellbutrin, let your doctor know. If necessary, they can suggest alternative treatments.

Thoughts or Actions Related to Suicide

Wellbutrin may cause suicidal thoughts or actions in certain individuals. The likelihood of experiencing this adverse effect increases when beginning Wellbutrin or after a dosage change.

In teenagers with depression and other mental illnesses, antidepressants like bupropion might raise the risk of suicidal ideation and actions.

Odd Thoughts or Actions

Delusions, hallucinations, and bewilderment are examples of aberrant ideas or conduct. For some people, drinking alcohol might cause these as well. Therefore, while on Wellbutrin, it is best to limit or abstain from alcohol use. Ask your doctor whether it is safe to drink any alcohol while on Wellbutrin.

Discuss any potential risks and side effects of Wellbutrin with your physician. They may advise you to take specific measures to mitigate your risk.

Are There Any Potential Interactions Between Wellbutrin and Bipolar Disorder?

Some items may have an interaction with Wellbutrin. Because of this, it’s crucial to inform your physician about any herbs, dietary supplements, or medicines you use. Additionally, Wellbutrin may alter how your body responds to these substances.

The following drugs, though not a comprehensive list, may interact with Wellbutrin:

• antipsychotics
• heart rhythm drugs
• Medications that raise the chance of having a seizure
• drugs that raise dopamine levels

Is It Possible to Use Wellbutrin for Bipolar Disorder While Pregnant?

If you are pregnant or may become pregnant, discuss the hazards and advantages of Wellbutrin with your physician. Since any medicine you take enters breast milk, it’s important to talk about breastfeeding.

When You Discontinue Wellbutrin Treatment for Bipolar Disorder, What Happens?

Never stop taking Wellbutrin without first speaking with your doctor or therapist. A premature cessation of the medication may result in a recurrence of depressive symptoms.

You could have physical and psychological side effects if you discontinue an antidepressant or reduce the dose too soon. As your body adjusts, these may settle.

If your bipolar disorder symptoms get worse or you experience any severe side effects, call your doctor right away. They might alter your dosage or search for alternative drugs.

Summary

An antidepressant drug called Wellbutrin raises the levels of mood-regulating neurotransmitters in the brain in order to alleviate depression. It is not approved by the FDA for the treatment of bipolar illness. But, it can be prescribed off-label by doctors to help treat depressive episodes in those with bipolar illness.

Wellbutrin, like other antidepressants, has the potential to induce side effects or negative responses. This includes the possibility of phase shifting, especially into episodes of hypomania or mania. To decide if Wellbutrin is the best course of treatment for you, speak with your physician about its advantages and hazards.

Never discontinue Wellbutrin without consulting your physician. A recurrence of your symptoms may result from abruptly stopping.