Does Tmg Lower Blood Pressure: Get Answers
Does Tmg Lower Blood Pressure: TMG supplements may help control insulin levels, enhance athletic performance, and strengthen the heart. Although taking up to 15 grams daily might not be harmful, vomiting and diarrhea are possible adverse effects. Benefits, adverse effects, dose, and ways to boost TMG consumption with diet are all covered in this article.

Trimethylglycine (TMG), sometimes referred to as betaine or betaine anhydrous, is a crucial antioxidant and anti-inflammatory substance that your body is capable of producing on its own. It can be found in supplements as well as foods like beetroot.
Glycine with three methyl groups attached is what TMG is made of. It participates in methylation, a chemical process that is necessary for the synthesis of DNA. It’s crucial to remember that TMG might have negative consequences, particularly when taken in large quantities.
Potential Benefits of Tmg
TMG supplements may be linked with several health benefits.
May Lower Homocysteine Levels to Improve Heart Health
TMG may aid in the conversion of the amino acid homocysteine into the different substance methionine. Given that elevated homocysteine levels may raise the risk of heart disease, this is advantageous.
Up to 4 grams (g) of TMG daily reduced homocysteine levels without adversely affecting blood pressure, lipid levels, or other heart-related parameters.
However, some studies discovered that TMG supplements can marginally raise blood levels of total and LDL (bad) cholesterol, which are risk factors for heart disease. In the end, further study is required to determine the potential effects of these supplements on heart health.
Could Improve Athletic Performance
TMG supplements are frequently used by athletes to improve their performance during workouts. In a 2021 study of 29 soccer players, it was discovered that using 2 g of TMG supplements for 14 weeks increased sprint repetition ability, running speed, and muscle strength.
Researchers from a 2014 review predict that TMG may, despite the fact that the precise processes are unknown:
- lessen weariness
- increase the synthesis of proteins
- enhance the production of creatine, a substance that gives your muscle cells energy.
Research on the possible advantages of TMG supplements for sports performance is conflicting. Only two of the seven research reviewed in 2017 indicated that taking TMG supplements improved muscle strength and power.
Similarly, using TMG supplements had no discernible effects on cross-fit training performance, according to a 2020 study. Before professionals can confidently suggest TMG supplements to improve athletics, more research is required.
May Prevent Insulin Resistance
TMG supplements may help with insulin resistance, a disorder that impairs your body’s capacity to use the hormone insulin to control blood sugar levels, according to several studies. A 2017 study including almost 2,400 participants linked reduced insulin resistance to increased betaine and choline consumption.
Additionally, giving TMG supplements to mice on a high-fat diet enhanced fat metabolism and reduced insulin resistance in a 2018 animal research. To learn more about how TMG might impact insulin resistance in people, more research is still required.
Could Improve Depression
According to certain research, TMG supplements may enhance the effectiveness of specific depressive drugs. TMG has specifically been demonstrated to enhance the effects of S-adenosyl-methionine (SAMe), a class of drug used to treat mild to moderate depression.
In a 2015 study with 64 depressed participants, those who took TMG and SAMe together for a year saw a bigger reduction in their symptoms than those who took SAMe alone. Additionally, TMG pills could lessen anxiety and depressive symptoms. TMG may help reduce the increased homocysteine levels associated with these illnesses.
Potential Side Effects
The most common side effects linked with TMG supplements are digestive issues, including:
- diarrhea
- indigestion
- bloating
- cramps
- nausea
- vomiting
If you’re taking larger dosages of the supplement, these are more frequent. Rarely, TMG may also produce a substantial rise in blood methionine levels, which may lead to fluid accumulation around the brain.
Stop using this product and consult a physician if you encounter any negative effects. Due to the lack of study on the safety and long-term health consequences of TMG supplements, it is not advised for children, pregnant women, or nursing mothers.
Dosage

The majority of products contain between 750 and 3,000 milligrams (mg) of TMG per serving, although there are no official dosage guidelines for TMG supplements. When taken in dosages of up to 20 g daily, TMG is regarded as safe.
The majority of research on the possible advantages of TMG supplements for people has employed daily dosages ranging from 500 to 9,000 mg, usually split up into multiple smaller doses.
Before taking a TMG supplement, consult your doctor if you have any underlying medical concerns or are already taking any drugs, and make sure to take them exactly as prescribed.
Other Ways to Increase Your Intake
You can increase your intake of TMG naturally, as it’s found in many meals. Here’s the amount of TMG found in a 3.5-ounce (100-g) serving of several foodstuffs, as per research from 2004:
- Wheat bran: 1,339 mg
- Wheat germ: 1,241 mg
- Spinach: 600 to 645 mg
- Quinoa: 390 mg
- Beets: 114 to 297 mg
- Shrimp: 219 mg
- Wheat bread: 201 mg
Several factors may impact the quantity of TMG in foods. Certain cooking methods, particularly boiling, significantly decrease the TMG content.
Takeaway
Lastly on Does Tmg Lower Blood Pressure, your body produces TMG, a substance that can be found in some foods and supplements. Studies on both humans and animals indicate that it may have anti-inflammatory and antioxidative qualities that could offer numerous advantages, but more research is required.
Remember that if you have a medical problem such as insulin resistance, depression, or heart disease, you should consult a healthcare provider before taking TMG supplements. The benefits require further investigation.